Dr. Eric T. Boder
Career Development Associate Professor
Ph.D., Illinois: Molecular biotechnology and bioengineering, protein engineering and directed evolution.
Brief Bio
Dr. Boder received his B.S. degree Summa Cum Laude in Chemical Engineering from Washington University in 1993 and earned M.S. and Ph.D. degrees in Chemical Engineering from the University of Illinois in 1996 and 1999, respectively. Dr. Boder's thesis research focused on molecular engineering of single-chain antibodies by yeast display and directed evolution. Following a short postdoc studying T cell immunology at National Jewish Medical and Research Center in Denver, CO, Dr. Boder joined the faculty in Chemical and Biomolecular Engineering at the University of Pennsylvania in 2000. In 2007, Dr. Boder joined the faculty at UT-Knoxville, where his research program focuses on protein engineering and applied molecular biology.
Research Areas
(Click each area for more information!)
Biomolecular engineering applications in immune function
Viral membrane fusion proteins
Molecular switching and cell adhesion proteins
Protein immobilizing and modifying enzymes
Selected Awards and Honors
2003 National Science Foundation CAREER Award
2002 NAE Frontiers of Engineering Invitee
Professional Activities
» American Institute of Chemical Engineers
» Society for Biological Engineering
» The Protein Society
» American Chemical Society
Selected Publications
L.R. Pepper, Y.K. Cho, E.T. Boder, and E.V. Shusta: "A decade of yeast surface display technology: Where are we now?" Comb. Chem. High Throughput Screen., 11:127-34 (2008).
R. Parthasarathy, S. Subramanian, and E.T. Boder: "Sortase A as a novel molecular “stapler” for sequence-specific protein conjugation." Bioconj. Chem., 18:469-476 (2007).
J.H. Lee, M. Goulian, and E.T. Boder: "Autocatalytic Activation of Influenza Hemagglutinin." J. Mol. Biol., 364:275-282 (2006).
L.R. Pepper, D.A. Hammer, and E.T. Boder: "Rolling Adhesion of αL I Domain Mutants Decorrelated from Binding Affinity." J. Mol. Biol., 360:37-44 (2006).
S. Park, Y. Xu, X.F. Stowell, F. Gai, J.G. Saven, and E.T. Boder: "Limitations of yeast surface display in engineering proteins of high thermostability." Prot. Eng. Des. Sel., 19:211-217 (2006).
Selected Patents
U.S. Patent 6,300,065 (2000): Yeast cell surface display of proteins and uses thereof
Contact Dr. Boder
437 Dougherty Engineering Bldg.
Department of Chemical and Biomolecular Engineering
University of Tennessee
Knoxville, TN 37996-2200
Tel: (865) 974-6362
Email: boder@utk.edu
Home page: http://web.utk.edu/~eboder/