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Faculty - Mingjun Zhang

Zhang

Mingjun Zhang
Associate Professor

408 Dougherty Engineering Building
University of Tennessee
Knoxville, TN 37996-2210
Office: (865)974-7620
Fax: (865)974-5274
Email: mjzhang@utk.edu

http://web.utk.edu/~mjzhang
Teaching ~ Education ~ Research Interests ~ Professional Experience ~ Professional Activities ~ Selected Publications

TEACHING

  • Micro/Nano-scale Science and Engineering for Bio-systems
  • Mathematical Modeling and Control for Bio-systems
  • Molecular Machinery and Systems Biology

EDUCATION

  • D.Sc., 2000, Washington University in St. Louis, MO, USA
  • Ph.D., 1996, Zhejiang University, P.R. China
  • MSBioE, 2007, Stanford University, CA, USA
  • MSEE, 2007, Stanford University, CA, USA
  • BSME, 1990, Zhenjiang University, P.R. China

RESEARCH INTERESTS (back to top)

Nano Biosystems and Nano Bio-mimetics. Nano-scale biological systems inspired technology and system theory, nano-scale adhesive and climbing mechanism, lab-on-a-chip, molecular diagnostics, bio-marker based controlled drug delivery, bio-sensors, modeling, tracking and control of nano biosystems.

We view molecular machinery as a complex system, employ system theory to understand cell bio-physical problems, and micro/nano-scale technology to control the machinery for biomedical applications.

Over the past several years, my research has focused on fundamental techniques that may help to explore the above interests, including mathematical modeling techniques for cell biology, micro/nano-scale bio-control mechanisms, bio-chip fabrication, lab-on-a-chip molecular diagnostics, biological con-focal microscopy and AFM.
 
I am currently working on inkjet technology enabled probe tips for bio-nano-applications, dynamics and feed forward control for biological molecular systems, game theoretical formulation of the biological immune system, integration of biological con-focal and AFM for understanding and controlling cell dynamics.

PROFESSIONAL EXPERIENCE (back to top)

2008-Present Associate Professor, Department of Mechanical, Aerospace and Biomedical Engineering, The University of Tennessee, Knoxville, TN 37996
2001-2007 Research and development for bio-chip fabrication, lab-in-a-chip molecular diagnostics and bio-instrumentation. Life Science and Chemical Analysis Division, Agilent Technologies, California, USA

PROFESSIONAL ACTIVITIES (back to top)

2006 Senior Member, IEEE
2006 Fellow, American Academy of Nanomedicine
2007 Lead Guest Editor, Special Issue on Drug Delivery Automation, IEEE Transactions on Automation Science and Engineering
2006 Lead Guest Editor, Special Issue on Automation for the Life Sciences, IEEE Transactions on Automation Science and Engineering
10/2004-present Member of the Editorial Board, Nanomedicine: Nanotechnology, Biology and Medicine
03/2004-02/2008 Associate Editor, IEEE Transactions on Automation Science and Engineering

SELECTED PUBLICATIONS (back to top)

W. Fisher and M. J. Zhang. DNA Bio-chip Microarray Fabrication System using Inkjet Technology, IEEE Trans Auto Sci and Eng, 4(4), pp. 488-500,  2007.

M. J. Zhang, W. M. Tao and P. A. Pianetta. Dynamics modeling of biolistic gene guns, Physics in Medicine and Biology, 52(5), pp. 1485-93, 2007.

I. Barbulovic-Nad, M. Lucente, Y. Sun, M. J. Zhang, A. R. Wheeler, M. Bussmann. A Review of Bio-chip Fabrication Techniques, Critical Review of Biotechnology, 26, pp. 237-259, 2006.

M. J. Zhang, O. Ma and X. Xiao. Dynamics Modeling and Analysis of Inkjet Technology Based Oligo DNA Microarray Spotting, IEEE Trans Auto Sci & Eng, 3(2), pp. 159-168, 2006.

M. J. Zhang, M. X. Cheng, and T. J. Tarn. A Mathematical Formulation of DNA Computation, IEEE Transactions On NanoBioscience, vol. 5, no. 1, pp. 32-40, 2006.

T. J. Tarn, P. Sanposh, D. Cheng, M. J. Zhang. Output Regulation for Nonlinear Systems: Some Recent Theoretical and Experimental Results, IEEE Trans Con Sys Tech, 13 (4), pp. 605-610, 2005.

M. J. Zhang, C. Sabharwal, W. M. Tao, T. J. Tarn, N. Xi and G. Y. Li. Interactive DNA sequence and structure design for DNA nano-applications, IEEE Transactions On NanoBioscience, 3 (4), pp. 286-292, 2004.

M. J. Zhang, T. J. Tarn. A Hybrid Switching Control Strategy for Nonlinear and Under-actuated Mechanical Systems, IEEE Trans Automatic Control, 48 (10), pp. 1777-1782, 2003.

T. J. Tarn, M. J. Zhang and A. Serrani. New Integrability Conditions for Differential Contraints, Systems and Control Letters, 49 (5), pp. 335-345, 2003.

M. J. Zhang and T. J. Tarn. Hybrid Control of the Pendubot, IEEE/ASME Transactions on Mechatronics, 7 (1), pp. 79-87, 2002.

Please click here to see more publications http://web.utk.edu/~mjzhang/publications.html

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